Isuprel Mistometer: Full Drug Profile
Isuprel Mistometer - General Information
Isopropyl analog of epinephrine; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant. [PubChem]
Pharmacology of Isuprel Mistometer
Isuprel Mistometer is a relatively selective beta2-adrenergic bronchodilator. Isuprel Mistometer is indicated for the relief of bronchospasm associated with chronic obstructive pulmonary disease. The pharmacologic effects of beta adrenergic agonist drugs, including Isuprel Mistometer, are at least in part attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the enzyme which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic- 3',5'- adenosine monophosphate (c-AMP). Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.
Isuprel Mistometer for patients
Isuprel Mistometer Interactions
Isoproterenol hydrochloride injection and epinephrine should not be administered simultaneously because both drugs are direct cardiac stimulants and their combined effects may induce serious arrhythmias. The drugs may, however, be administered alternately provided a proper interval has elapsed between doses.
ISUPREL should be used with caution, if at all, when potent inhalational anesthetics such as halothane are employed because of potential to sensitize the myocardium to effects of sympathomimetic amines.
Isuprel Mistometer Contraindications
Use of isoproterenol hydrochloride injection is contraindicated in patients with tachyarrhythmias; tachycardia or heart block caused by digitalis intoxication; ventricular arrhythmias which require inotropic therapy; and angina pectoris.
Additional information about Isuprel Mistometer
Isuprel Mistometer Indication: For the treatment of mild or transient episodes of heart block that do not require electric shock or pacemaker therapy also used in management of asthma and chronic bronchitis Mechanism Of Action: The pharmacologic effects of isoproterenol are at least in part attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic AMP. Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Isoproterenol Synonyms: IPA; Epinephrine Isopropyl Homolog; Isopropyladrenaline; Isopropylarterenol; Isopropylnoradrenaline; Isopropylnorepinephrine; Isoproterenol Chloride; Isoproterenol HCl; L-Isopropylnoradrenaline; L-Isoproterenol; N-Isopropylnoradrenaline; N-Isopropylnorepinephrine; Isopropydrin; Isoprenalin; Isoprenaline Drug Category: Cardiotonic Agents; Bronchodilator Agents; Sympathomimetic Drug Type: Small Molecule; Approved Other Brand Names containing Isoproterenol: Aerolone; Aleudrin; Aleudrine; Aludrin; Aludrine; Asiprenol; Asmalar; Assiprenol; Bellasthman; Bronkephrine; Euspiran; Isadrine; Isonorene; Isonorin; Isorenin; Isuprel; Isuprel Mistometer; Isupren; Medihaler-Iso; Neo-Epinine; Neodrenal; Norisodrine; Norisodrine Aerotrol; Novodrin; Proternol; Respifral; Saventrine; Vapo-Iso; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: Not Available Biotransformation: Not Available Half Life: Not Available Dosage Forms of Isuprel Mistometer: Liquid TopicalGel TopicalLiquid Auricular (otic)Spray TopicalLotion TopicalSwab TopicalSolution IntramuscularStick TopicalSolution Topical Chemical IUPAC Name: 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol Chemical Formula: C11H17NO3 Isoproterenol on Wikipedia: https://en.wikipedia.org/wiki/Isoproterenol Organisms Affected: Humans and other mammals